With a legacy of delays and cost overruns, the National Ignition Facility was wryly nicknamed the “National Almost Ignition Facility,” or “ NAIF,” by critics in Congress. Abrams used it to portray the warp core of the USS Enterprise in “Stark Trek Into Darkness.” The very middle of this target chamber becomes the hottest place in the solar system every time they run a fusion experiment, and it is covered with enough gleaming machinery that J.J. Running across the soaring white ceilings are miles of square tubes holding 192 of the most energetic lasers in the world, all snaking toward a round room at the center. Ma’s office is a giant box of lasers the size of three football fields in the corner of a 7,000-acre lab in Livermore. Nuclear fusion: How long until this breakthrough discovery can power your house
Therefore, an approach using the selective approach of stone-dissolution capsules will help to develop alternative urolithiasis treatments to the conventional surgical and systemic dissolution approaches.NIF's target chamber is where the magic happens - temperatures of 100 million degrees and pressures extreme enough to compress the target to densities up to 100 times the density of lead are created there. In the end, more than 50% of stone, even in surgically tricky regions, was removed by 10 repeated treatments. Eventually, the potential removal of urolithiasis in the body was verified using a PDMS-based ureter-imitated chip with a human kidney stone (CaOx 100%, 5–7 mm size) was located in the minor calyx under an artificial urine counter flow (0.5 mL min−1). Using a double-droplet microfluidics method, hexametaphosphate (HMP) chelating solution was encapsulated in an Fe3O4 nanoparticle (Fe3O4 NP)-loaded PLGA polymer shell with a thickness of 90%), and an effective removal efficacy (>95 %, 7 repeat cycles) of artificial calcium oxalate (5 mm in size) via a chelating effect. A novel urolithiasis treatment in which chelating solution encapsulated in poly(lactic-co-glycolic acid PLGA)-based microcapsules was delivered magnetically to specific urolithiasis sites and then subjected to ultrasound (US) to release the chelating solution and dissolve the stones.
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